Clobex® Spray – Class I Power

Highest Success Rate Available

Clobex® (clobetasol propionate) Spray, 0.05% delivers significant, visible improvement for the scaling, erythema and plaque thickening of psoriasis. Plus, the easy application encourages patient compliance.

In a clinical study with 120 patients with moderate to severe plaque psoriasis, 82% became clear or almost clear at 4 weeks of treatment.1

  • In as early as 2 weeks, 47% of patients achieved clear or almost clear rates1
  • Almost 60% of the study participants maintained success at 4 weeks post-treatment1
    • No other therapy was used during the post-treatment phase
  • The majority of adverse events reported were mild to moderate and transient

Comparable results were found in a separate study with 120 patients, with 78% of patients clear or almost clear at 4 weeks, which confirmed that 8 out of 10 patients on average were clear or almost clear after 4 weeks of therapy with Clobex® Spray.


A 4-week, multicenter, randomized, double-blind, vehicle-controlled, parallel-group study of patients with moderate to severe plaque psoriasis to evaluate the efficacy and safety of clobetasol propionate spray, 0.05%. Patients applied either of clobetasol propionate spray, 0.05% BID (n=60) or its vehicle BID (n=60).
*P<0.001 vs vehicle.

Patients using Clobex® Spray should:

  • Not cover or bandage the treated skin unless directed by the physician
  • Not use it on the face, underarms or groin area
  • Wash their hands after applying the medication if any gets on their hands

See important efficacy, safety and prescribing information for Clobex® Shampoo and Clobex® Lotion

Reference:

  1. 1. Clobex® Spray Prescribing Information. October 2005. Galderma Laboratories, L.P.
Find a Dermatologist     Zip Code (first three digits only):  
 

Clobetasol propionate has been shown to suppress the HPA axis at the lowest doses tested. In controlled clinical trials, the following adverse reactions have been reported: burning, pruritus, dryness, pain, hyperpigmentation around resolving plaque, irritation and atrophy.

Clobex® (clobetasol propionate) Spray, 0.05% is not recommended for use on anyone younger than 18 years of age. Treatment should be limited to 4 consecutive weeks. The total dosage should not exceed 50 g (59 mL or 2 fl oz) per week. Patients should use Clobex® (clobetasol propionate) Spray, 0.05%, only for the minimum period necessary to achieve desired results. Clobex® (clobetasol propionate) Spray, 0.05% should not be used on the face, groin, or axillae.

See full prescribing information for Clobex® Spray, Clobex® Lotion and Clobex® Shampoo.